Xenograft of microencapsulated Sertoli cells restores glucose homeostasis in db/db mice with spontaneous diabetes mellitus

@article{Luca2016XenograftOM,
  title={Xenograft of microencapsulated Sertoli cells restores glucose homeostasis in db/db mice with spontaneous diabetes mellitus},
  author={G. Luca and I. Arato and F. Mancuso and M. Calvitti and G. Falabella and G. Murdolo and G. Basta and D. F. Cameron and B. Hansen and F. Fallarino and T. Baroni and M. Aglietti and C. Tortoioli and M. Bodo and R. Calafiore},
  journal={Xenotransplantation},
  year={2016},
  volume={23},
  pages={429 - 439}
}
Increased abdominal fat and chronic inflammation in the expanded adipose tissue of obesity contribute to the development of insulin resistance and type 2 diabetes mellitus (T2D). The emerging immunoregulatory and anti‐inflammatory properties of Sertoli cells have prompted their application to experimental models of autoimmune/inflammatory disorders, including diabetes. 
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