Xenograft of microencapsulated Sertoli cells restores glucose homeostasis in db/db mice with spontaneous diabetes mellitus.

@article{Luca2016XenograftOM,
  title={Xenograft of microencapsulated Sertoli cells restores glucose homeostasis in db/db mice with spontaneous diabetes mellitus.},
  author={G. De Luca and Iva Arato and Francesca V. Mancuso and Mario Calvitti and G Fernanda Falabella and Giuseppe Murdolo and Giuseppe Basta and Don Cameron and Barbara C Hansen and Francesca Fallarino and Tiziano Baroni and Maria Chiara Aglietti and Cristina Tortoioli and M. Wernli. E. Bodo and Riccardo Calafiore},
  journal={Xenotransplantation},
  year={2016},
  volume={23 6},
  pages={
          429-439
        }
}
  • G. De Luca, Iva Arato, +12 authors Riccardo Calafiore
  • Published 2016
  • Biology, Medicine
  • Xenotransplantation
  • BACKGROUND Increased abdominal fat and chronic inflammation in the expanded adipose tissue of obesity contribute to the development of insulin resistance and type 2 diabetes mellitus (T2D). The emerging immunoregulatory and anti-inflammatory properties of Sertoli cells have prompted their application to experimental models of autoimmune/inflammatory disorders, including diabetes. The main goal of this work was to verify whether transplantation of microencapsulated prepubertal porcine Sertoli… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 27 REFERENCES

    Transdifferentiation properties of adipocytes in the adipose organ.

    • Saverio Cinti
    • Medicine, Biology
    • American journal of physiology. Endocrinology and metabolism
    • 2009
    VIEW 2 EXCERPTS

    Recent Advances in Obesity-Induced Inflammation and Insulin Resistance

    VIEW 10 EXCERPTS
    HIGHLY INFLUENTIAL

    Microparticle-loaded neonatal porcine Sertoli cells for cell-based therapeutic and drug delivery system.

    VIEW 2 EXCERPTS