Xenograft model of progressive human proliferative breast disease.

@article{Miller1993XenograftMO,
  title={Xenograft model of progressive human proliferative breast disease.},
  author={F. Roy Miller and Herbert D. Soule and Larry R. Tait and Robert Joseph Pauley and Sandra R. Wolman and P. J. Dawson and Gloria H. Heppner},
  journal={Journal of the National Cancer Institute},
  year={1993},
  volume={85 21},
  pages={
          1725-32
        }
}
BACKGROUND Progression of proliferative breast disease has been associated with increased risk for development of invasive carcinoma. Cell lines have been developed to facilitate the study of this process. Human cell line MCF10A originated from spontaneous immortalization of breast epithelial cells obtained from a patient with fibrocystic disease, and cell lines MCF10AneoN and MCF10AneoT were created by stable transfection of these cells with the neomycin-resistance gene and either the HRAS… CONTINUE READING
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