Xenograft growth and histodifferentiation of squamous cell carcinomas of the pharynx and larynx.

@article{Chen1996XenograftGA,
  title={Xenograft growth and histodifferentiation of squamous cell carcinomas of the pharynx and larynx.},
  author={Jiangli Chen and George E. Milo and Charles F. Shuler and David E. Schuller},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={1996},
  volume={81 2},
  pages={197-202}
}
The potential for growth in a xenogeneic host and the pattern of histodifferentiation was examined in 56 human squamous cell carcinomas of the pharynx and larynx transplanted to nude mice. Among these 56 transplanted tumors, 13 of 36 primary and 12 of 20 metastatic tumors were found to be tumorigenic in nude mice. Eleven of 24 pharyngeal and 14 of 32 laryngeal tumors grew in nude mice. The dynamics of transplanted tumor growth in the surrogate host took place independent of the tumor grade and… CONTINUE READING
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