Xenoestrogens: mechanisms of action and detection methods

  title={Xenoestrogens: mechanisms of action and detection methods},
  author={Stefan O. Mueller},
  journal={Analytical and Bioanalytical Chemistry},
  • S. O. Mueller
  • Published 1 February 2004
  • Biology, Chemistry
  • Analytical and Bioanalytical Chemistry
Estrogenic compounds exert pleiotropic effects in wildlife and humans, and endogenous estrogens, like 17β-estradiol, regulate growth and development of their target tissues. Environmental, industrial, or naturally occurring chemicals that possess estrogenic and/or antiestrogenic activities are termed xenoestrogens and may interfere with endocrine systems. These xenoestrogens are therefore defined as endocrine-active or endocrine-disrupting compounds. The estrogen receptor (ER) is the major… 
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