Xenoduplex analysis--a method for comparative gene mapping using hybrid panels.

@article{Marklund1998XenoduplexAM,
  title={Xenoduplex analysis--a method for comparative gene mapping using hybrid panels.},
  author={Lena Marklund and Jin Tae Jeon and Leif Andersson},
  journal={Genome research},
  year={1998},
  volume={8 4},
  pages={399-403}
}
Somatic cell hybrid (SCH) panels and radiation hybrid (RH) panels are powerful resources for comparative gene mapping because gene assignments are made without the detection of genetic polymorphism as needed for linkage mapping. A frequently encountered problem, however, is that the gene specific primers may amplify homologous PCR products of equal length… CONTINUE READING