Xenobiotic biotransformation in the Pacific oyster (Crassostrea gigas).

  title={Xenobiotic biotransformation in the Pacific oyster (Crassostrea gigas).},
  author={Daniel Schlenk and Donald R. Buhler},
  journal={Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology},
  volume={94 2},
1. Oyster visceral mass and gill tissues possessed measurable flavin-containing monooxygenase (FMO) activity. 2. FMO activity was confirmed in visceral mass microsomes by oxygen uptake experiments utilizing various nitrogen and sulfur-containing chemicals along with measurement of N,N-dimethylaniline (DMA) N-oxidase and methimazole oxidation activities. DMA N-oxidase and methimazole oxidation activities also were present in gill microsomes. 3. Excluding oyster gill methimazole oxidation, there… CONTINUE READING