Xeno-Free Defined Conditions for Culture of Human Embryonic Stem Cells, Neural Stem Cells and Dopaminergic Neurons Derived from Them

@inproceedings{Swistowski2009XenoFreeDC,
  title={Xeno-Free Defined Conditions for Culture of Human Embryonic Stem Cells, Neural Stem Cells and Dopaminergic Neurons Derived from Them},
  author={Andrzej Swistowski and Jun Peng and Yi Han and Anna Maria Swistowska and Mahendra S. Rao and Xianmin Zeng},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND Human embryonic stem cells (hESCs) may provide an invaluable resource for regenerative medicine. To move hESCs towards the clinic it is important that cells with therapeutic potential be reproducibly generated under completely defined conditions. METHODOLOGY/PRINCIPAL FINDINGS Here we report a four-step scalable process that is readily transferable to a Good Manufacture Practice (GMP) facility for the production of functional dopaminergic neurons from hESCs for potential clinical… CONTINUE READING