Xanthurenic acid derivative formation in the lens is responsible for senile cataract in humans

Abstract

• Background: The tryptophan degradation pathway leads to NAD production via 3-hydroxykynurenine. Kynurenine aminotransferase (KAT) transforms 3-hydroxykynurenine into xanthurenic acid. In this study, we measured the activity of KAT in human lenses and studied the consequences of xanthurenic acid formation • Methods: KAT activity was determined by the… (More)
DOI: 10.1007/BF00189352

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Cite this paper

@article{Malina1996XanthurenicAD, title={Xanthurenic acid derivative formation in the lens is responsible for senile cataract in humans}, author={Halina Zofia Malina and Xavier Daniel Martin}, journal={Graefe's Archive for Clinical and Experimental Ophthalmology}, year={1996}, volume={234}, pages={723-730} }