Xanthine oxidase inhibitors from the leaves of Lagerstroemia speciosa (L.) Pers.

@article{Unno2004XanthineOI,
  title={Xanthine oxidase inhibitors from the leaves of Lagerstroemia speciosa (L.) Pers.},
  author={Tomonori Unno and Akio Sugimoto and Takami Kakuda},
  journal={Journal of ethnopharmacology},
  year={2004},
  volume={93 2-3},
  pages={391-5}
}
Xanthine oxidase (XOD) is a key enzyme playing a role in hyperuricemia, catalyzing the oxidation of hypoxanthine to xanthine and then to uric acid. This study aimed to identify the XOD inhibitors from the leaves of Lagerstroemia speciosa (L.) Pers. (Lythraceae), which was traditionally used as a folk medicine in the Philippines. Using a bioassay-guided fractionation technique, two active compounds were isolated from the aqueous extracts of the Lagerstroemia speciosa leaves, namely valoneic acid… CONTINUE READING