Xanthine oxidase inactivation by reagents that modify thiol groups.

Abstract

1. The presence of xanthine was required for the inhibition of bovine milk xanthine oxidase by o-iodosobenzoate, iodoacetamide, hydrogen peroxide or p-chloromercuribenzoate. 2. Inactivation by p-chloromercuribenzoate was very rapid, was reversed by cysteine and was less in the presence of FAD. Lineweaver-Burk plots showed that the inactivation by p… (More)

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@article{Green1967XanthineOI, title={Xanthine oxidase inactivation by reagents that modify thiol groups.}, author={Rosalyn C Green and Peter James O'Brien}, journal={The Biochemical journal}, year={1967}, volume={105 2}, pages={585-9} }