Xanthine Oxidase and its Role as Target in Cardiovascular Disease: Cardiovascular Protection by Enzyme Inhibition?

@article{Schuchardt2017XanthineOA,
  title={Xanthine Oxidase and its Role as Target in Cardiovascular Disease: Cardiovascular Protection by Enzyme Inhibition?},
  author={Mirjam Schuchardt and Jaqueline Herrmann and Markus Tolle and Markus van der Giet},
  journal={Current pharmaceutical design},
  year={2017},
  volume={23 23},
  pages={
          3391-3404
        }
}
BACKGROUND Formerly, hyperuricemia was mainly restricted to the rich population, but now-a-days it is a condition affecting wide parts of western civilization. Although only a minority of our population develops clinically relevant symptomatic hyperuricemia, there is growing evidence that elevated serum uric acid levels might be associated with elevated cardiovascular risk and cardiovascular disease progression. But it is not clear whether uric acid is just a biomarker or exerts detrimental… CONTINUE READING