Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus.

Abstract

Lower vertebrates develop a unique set of primary sensory neurons located in the dorsal spinal cord. These cells, known as Rohon-Beard (RB) sensory neurons, innervate the skin and mediate the response to touch during larval stages. Here we report the expression and function of the transcription factor Xaml1/Runx1 during RB sensory neurons formation. In… (More)
DOI: 10.1016/j.ydbio.2011.11.016

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