XYY chromosomal complement, proven by fluorescence, in a child with trisomy 21: 48,XYY,21+


Clinical, cytogenetic, autoradiographic, fluorescence microscopic and dermatoglyphic data of a boy with 48,XYY,21+ karyotype are reported. The child had some clinical anomalies common in Down's syndrome. DNA replication of the 2 Y chromosomes was synchronous in all labelled metaphases. It was possible to distinguish the two Y's from the pairs No. 21-22… (More)
DOI: 10.1007/BF00295795


5 Figures and Tables