XRCC1 polymorphisms and risk of colorectal cancer: a meta-analysis

  title={XRCC1 polymorphisms and risk of colorectal cancer: a meta-analysis},
  author={Bin Wang and Dan Wang and Gang Huang and Chao Zhang and Dong-hua Xu and Wei-ping Zhou},
  journal={International Journal of Colorectal Disease},
Previous studies investigating the association between X-ray repair cross-complementation group 1 (XRCC1) polymorphisms and colorectal cancer (CRC) risk has provided inconsistent results. The aim of our study was to clarify the effects of XRCC1variants on CRC risk. We conducted searches of the published literature in PubMed, Embase, and CBM databases up to July 6, 2009. Meta-analysis was performed by critically reviewing 14 studies with a total of 2,776 CRC cases and 4,402 controls on Arg399Gln… CONTINUE READING


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