XRCC1 Arg399Gln and Arg194Trp Polymorphisms and Risk of Systemic Lupus Erythematosus in an Iranian Population: A Pilot Study

@inproceedings{Salimi2014XRCC1A,
  title={
XRCC1 Arg399Gln and Arg194Trp Polymorphisms and Risk of Systemic Lupus Erythematosus in an Iranian Population: A Pilot Study},
  author={Saeedeh Salimi and Milad Mohammadoo-Khorasani and Ehsan Tabatabai and Mahnaz Sandoughi and Zahra Zakeri and Anoosh Naghavi},
  booktitle={BioMed research international},
  year={2014}
}
BACKGROUND Evidences are suggesting that DNA damage is implicated in development of systemic lupus erythematosus (SLE). Therefore we focused on two common XRCC1 polymorphisms (Arg399Gln and Arg194Trp) in SLE susceptibility in South East of Iran. METHODS Peripheral blood DNA was extracted from 163 SLE patients and 180 healthy controls. PCR-restriction fragment length polymorphism method was used for genotyping of XRCC1 Arg399Gln and Arg194Trp polymorphisms. RESULTS The frequency of Arg/Gln… CONTINUE READING

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XRCC1 genetic polymorphism Arg399Gln and hepatocellular carcinoma risk: a meta-analysis.

Liver international : official journal of the International Association for the Study of the Liver • 2011
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