XPA-210: a new proliferation marker to characterize tumor biology and progression of renal cell carcinoma

@article{Gakis2010XPA210AN,
  title={XPA-210: a new proliferation marker to characterize tumor biology and progression of renal cell carcinoma},
  author={Georgios Gakis and Joerg Hennenlotter and Marcus Scharpf and Joachim Hevler and David Schilling and Ursula Kuehs and Arnulf Stenzl and Christian Schwentner},
  journal={World Journal of Urology},
  year={2010},
  volume={29},
  pages={801-806}
}
Recent lung cancer data have shown an association of XPA-210, a key peptide of thymidine kinase, with advanced disease. We thus assessed its proliferation status in primary (M0) and metastatic (M1) renal cell carcinoma (RCC). Paraffin slides from 30 patients (mean age: 61.2 years; range: 42–84) with clear-cell RCC (M0 in 10; non-osseous M1 in 10; osseous M1 in 10) were T-matched for pT1/pT3. Corresponding malignant and benign renal parenchyma were immunohistochemically stained against XPA-210… CONTINUE READING

4 Figures & Tables

Connections & Topics

Mentioned Connections BETA
XPA-210 : a new proliferation marker to characterize tumor biology and progression of renal cell carcinoma .
In all RCC tissues , XPA-210 staining was significantly higher in the nucleus than in cytoplasm , potentially owing to large cytoplasmatic spaces as a characteristic histologic feature of clear - cell component .
In all RCC tissues , XPA-210 staining was significantly higher in the nucleus than in cytoplasm , potentially owing to large cytoplasmatic spaces as a characteristic histologic feature of clear - cell component .
XPA-210 : a new proliferation marker to characterize tumor biology and progression of renal cell carcinoma .
In all RCC tissues , XPA-210 staining was significantly higher in the nucleus than in cytoplasm , potentially owing to large cytoplasmatic spaces as a characteristic histologic feature of clear - cell component .
All Topics