XMRV: a new virus in prostate cancer?

  title={XMRV: a new virus in prostate cancer?},
  author={Amanda L. Aloia and Karen S Sfanos and William B Isaacs and Qizhi Zheng and Frank M Maldarelli and Angelo M De Marzo and Alan Rein},
  journal={Cancer research},
  volume={70 24},
Several recent articles have reported the presence of a gammaretrovirus, termed "XMRV" (xenotropic murine leukemia virus-related virus) in prostate cancers (PCa). If confirmed, this could have enormous implications for the detection, prevention, and treatment of PCa. However, other articles report failure to detect XMRV in PCa. We tested nearly 800 PCa samples, using a combination of real-time PCR and immunohistochemistry (IHC). The PCR reactions were simultaneously monitored for amplification… CONTINUE READING


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