XMAP230 is required for the organization of cortical microtubules and patterning of the dorsoventral axis in fertilized Xenopus eggs.

@article{Cha1999XMAP230IR,
  title={XMAP230 is required for the organization of cortical microtubules and patterning of the dorsoventral axis in fertilized Xenopus eggs.},
  author={Byeong Jin Cha and David L. Gard},
  journal={Developmental biology},
  year={1999},
  volume={205 2},
  pages={275-86}
}
The dorsoventral axis of Xenopus embryos is specified by a rotation of the egg cortex relative to the underlying yolky cytoplasm. This cortical rotation, which occurs during the first cell cycle after fertilization, is dependent upon an array of parallel microtubules in the subcortical cytoplasm. We have used confocal immunofluorescent microscopy and microinjection of affinity-purified anti-XMAP230 antibody to address the role of XMAP230, one of three high-molecular-weight microtubule… CONTINUE READING