X-ray structure of a voltage-dependent K+ channel

@article{Jiang2003XraySO,
  title={X-ray structure of a voltage-dependent K+ channel},
  author={Youxing Jiang and A. Lee and Jiayun Chen and V. Ruta and M. Cadene and B. Chait and R. MacKinnon},
  journal={Nature},
  year={2003},
  volume={423},
  pages={33-41}
}
Voltage-dependent K+ channels are members of the family of voltage-dependent cation (K+, Na+ and Ca2+) channels that open and allow ion conduction in response to changes in cell membrane voltage. This form of gating underlies the generation of nerve and muscle action potentials, among other processes. Here we present the structure of KvAP, a voltage-dependent K+ channel from Aeropyrum pernix. We have determined a crystal structure of the full-length channel at a resolution of 3.2 Å, and of the… Expand
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Voltage-Gated K+ Channels
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