X-linked mental retardation

@article{Ropers2005XlinkedMR,
  title={X-linked mental retardation},
  author={Hans-Hilger Ropers and Ben C. J. Hamel},
  journal={Nature Reviews Genetics},
  year={2005},
  volume={6},
  pages={46-57}
}
Genetic factors have an important role in the aetiology of mental retardation. However, their contribution is often underestimated because in developed countries, severely affected patients are mainly sporadic cases and familial cases are rare. X-chromosomal mental retardation is the exception to this rule, and this is one of the reasons why research into the genetic and molecular causes of mental retardation has focused almost entirely on the X-chromosome. Here, we review the remarkable recent… Expand

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