X-linked dilated cardiomyopathy. Novel mutation of the dystrophin gene.

@article{Franz1995XlinkedDC,
  title={X-linked dilated cardiomyopathy. Novel mutation of the dystrophin gene.},
  author={W. M. Franz and Marion Cremer and Raymond W. Herrmann and Ekkehard Gruenig and Wolfgang Fogel and Thomas Scheffold and Hans Hilmar Goebel and Renate Kircheisen and Wolfgang Dr Kuebler and Thomas Voit},
  journal={Annals of the New York Academy of Sciences},
  year={1995},
  volume={752},
  pages={
          470-91
        }
}
We report on a family with a severe form of X-linked dilated cardiomyopathy (DCM). Two brothers, the elder requiring heart transplantation, and a maternal cousin presented elevated creatine kinase levels, increased right ventricular diameters and electrocardiographic abnormalities. All complained of exertional cramping myalgia, but none had muscle weakness or a pathological electromyogram. Muscle biopsies of these individuals revealed a mild myopathic picture with atrophic type I and… CONTINUE READING

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