X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body

@inproceedings{Stichelen2014XinactivationNO,
  title={X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body},
  author={St{\'e}phanie Olivier-Van Stichelen and John A Hanover},
  booktitle={Front. Genet.},
  year={2014}
}
O-GlcNAc Transferase (OGT) catalyzes protein O-GlcNAcylation, an abundant and dynamic nuclear and cytosolic modification linked to epigenetic regulation of gene expression. The steady-state levels of O-GlcNAc are influenced by extracellular glucose concentrations suggesting that O-GlcNAcylation may serve as a metabolic sensor. Intriguingly, human OGT is… CONTINUE READING