X chromosome gene expression in human tissues: male and female comparisons.

@article{Talebizadeh2006XCG,
  title={X chromosome gene expression in human tissues: male and female comparisons.},
  author={Zohreh Talebizadeh and Patricia Kameri-mbote and Merlin G. Butler},
  journal={Genomics},
  year={2006},
  volume={88 6},
  pages={
          675-681
        }
}
About 25% of X-linked genes may escape inactivation at least to some degree. However, in vitro results from somatic cell hybrids may not reflect what happens in vivo. Therefore, we analyzed the female/male (F/M) gene fold expression ratio for 299 X-linked and 7795 autosomal genes from 11 different tissues from an existing in vivo microarray database. On average 5.1 and 4.9% of genes showed higher expression in females compared with 7.4 and 7.9% in males, respectively, for X-linked and autosomal… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 20 REFERENCES

No longer 'all-or-none'.

  • European journal of human genetics : EJHG
  • 2005
VIEW 2 EXCERPTS

The DNA sequence of the human X chromosome

Mark T. Ross, Darren V. Grafham, +279 authors David R. Bentley
  • Nature
  • 2005
VIEW 2 EXCERPTS

V

D. A. Kleinjan
  • van Heyningen, Long-range control of gene expression: emerging mechanisms and disruption in disease, Am. J. Hum. Genet. 76
  • 2005
VIEW 1 EXCERPT

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