X-Ray Phase Nanotomography Resolves the 3D Human Bone Ultrastructure

  title={X-Ray Phase Nanotomography Resolves the 3D Human Bone Ultrastructure},
  author={Max Langer and Alexandra Pacureanu and Heikki Suhonen and Quentin Grimal and Peter Cloetens and Françoise Peyrin},
  booktitle={PloS one},
Bone strength and failure are increasingly thought to be due to ultrastructural properties, such as the morphology of the lacuno-canalicular network, the collagen fiber orientation and the mineralization on the nanoscale. However, these properties have not been studied in 3D so far. Here we report the investigation of the human bone ultrastructure with X-ray phase nanotomography, which now provides the required sensitivity, spatial resolution and field of view. The 3D organization of the lacuno… CONTINUE READING
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