X-Chromosome dosage compensation.

  • Barbara J Meyer
  • Published 2005 in
    WormBook : the online review of C. elegans…


In mammals, flies, and worms, sex is determined by distinctive regulatory mechanisms that cause males (XO or XY) and females (XX) to differ in their dose of X chromosomes. In each species, an essential X chromosome-wide process called dosage compensation ensures that somatic cells of either sex express equal levels of X-linked gene products. The strategies… (More)


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