Wrapping it up: the cell biology of myelination

  title={Wrapping it up: the cell biology of myelination},
  author={M. Simons and J. Trotter},
  journal={Current Opinion in Neurobiology},
  • M. Simons, J. Trotter
  • Published 2007
  • Biology, Medicine
  • Current Opinion in Neurobiology
  • During nervous system development, oligodendroglia in the central nervous system (CNS) and Schwann cells in the peripheral nervous system (PNS) synthesise large amounts of specific proteins and lipids to generate myelin, a specialised membrane that spirally ensheathes axons and facilitates fast conduction of the action potential. Myelination is initiated after glial processes have attached to the axon and polarisation of the plasma membrane has been triggered. Myelin assembly is a multi-step… CONTINUE READING
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