Corpus ID: 30737784

Wounds Historical Findings in Horses That Developed Purpura Hemorrhagica

@inproceedings{Wiedner2006WoundsHF,
  title={Wounds Historical Findings in Horses That Developed Purpura Hemorrhagica},
  author={Ellen B. Wiedner and Laurent L Cou{\"e}til and Michel L{\'e}vy and Janice E. Sojka},
  year={2006}
}
pura hemorrhagica, results from inflammation and injury to the small blood vessels of the skin caused by deposition of antigen–antibody complexes within the blood vessels. The consequence of this injury is leakage of large proteins, electrolytes, and fluid from the vessels. In addition, extravasation of erythrocytes through vessel walls causes nonthrombocytopenic petechiations (i.e., purpura), which are common on the mucous membranes of affected horses. The former names for purpura hemorrhagica… Expand

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References

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Immune complexes in purpura hemorrhagica of the horse contain IgA and M antigen of Streptococcus equi.
TLDR
This work has detected and characterized immune complexes in the sera of horses with poststrangles purpura hemorrhagica by using PEG precipitation and Western blot analysis, and found equi-specific antigens similar to those found in acid extracts. Expand
Anaphylactoid Purpura in a Horse
TLDR
An 8-year-old gelding with a long-standing, streptococcal respiratory infection developed dyspnoea and colic and had massive necrosis and hemorrhage with a leucocytoclastic vasculitis in adjacent tissue which resembled anaphylactoid purpura in man. Expand
Infarctive purpura hemorrhagica in five horses.
TLDR
Five horses appeared to have a severe form of purpura hemorrhagica resembling Henoch-Schönlein purpURA in humans and characterized by infarction of skeletal muscles, which led to euthanatized. Expand
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TLDR
Therapy with immunosuppressive doses of corticosteroids, and in one case cyclophosphamide, resulted in prompt amelioration of the underlying inflammatory process, although regions of skin deprived of their blood supply eventually became necrotic and sloughed. Expand
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TLDR
It is shown, that the clinical picture of this disease has not changed within the last 150 years and the main haematological findings are neutrophilia, mostly going along with shift to the left and lymphopenia. Expand
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TLDR
The case histories of 18 horses with hindlimb lameness attributed to fibrotic myopathy were reviewed and 1 was free of lameness, 7 had various degrees of improvement, and 1 had no improvement. Expand
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TLDR
Forty-nine of the horses with purpura haemorrhagica survived, one died and three were euthanased, either because their severe clinical disease failed to respond to treatment or because they developed secondary complications. Expand
Urticaria, Blue Nose and Purpura Haemorrhagica in Horses
SUMMARY The etiological factors, clinical manifestations and treatment of urticaria, blue nose and purpura haem-orrhagica in the horse are discussed. RESUME Les facteurs etiologiques,Expand
Renal dysfunction in a case of purpura haemorrhagica in a horse
TLDR
Autopsy revealed membrano- and mesangial proliferative glomerulonephritis and chronic pleuritis and Circulating immune complexes may have been responsible for the renal diseases and the purpura. Expand
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TLDR
Seven horses with cutaneous vasculitis had history of, or were exposed to horses with, abscessed peripheral lymph nodes and likely were suffering from equine purpura hemorrhagica, and the only significant clinical or laboratory abnormality predictive of poor prognosis was fever. Expand
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