Wound healing is not impaired in rats undergoing perioperative treatment with the antineoplastic agent taurolidine.

@article{Braumann2008WoundHI,
  title={Wound healing is not impaired in rats undergoing perioperative treatment with the antineoplastic agent taurolidine.},
  author={Chris Braumann and N. D. Guenther and Jana Pohlenz and Rolf W. Pfirrmann and Charalambos Menenakos},
  journal={European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes},
  year={2008},
  volume={42 2},
  pages={
          91-6
        }
}
BACKGROUND/AIM The aim of this study was to determine whether an intravenous or an intraperitoneal application of the antineoplastic agent taurolidine (TRD) impairs wound healing in the absence of tumor load in rats. METHODS Eighty rats were randomized into eight groups (n = 10). Median laparotomy was performed in all animals. Three groups were treated by intravenous injection and three groups by local administration using a central port catheter system. For each group, 1 ml was applied… CONTINUE READING

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