Would the elderly be better off if they were given more placebos?

@article{Cherniack2010WouldTE,
  title={Would the elderly be better off if they were given more placebos?},
  author={E. Paul Cherniack},
  journal={Geriatrics \& Gerontology International},
  year={2010},
  volume={10}
}
  • E. Cherniack
  • Published 1 April 2010
  • Medicine
  • Geriatrics & Gerontology International
Placebos are useful in the medical care of the elderly, although the exact definition of a “placebo” or “placebo effect” is difficult to define precisely. They have an important role as control treatments in research trials, but a non‐specific “placebo effect” may also be beneficial part of many physician–patient interactions. Physicians also give them deliberately according to several studies worldwide to satisfy patient demands or because they believe in a “placebo effect” among other reasons… 
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References

SHOWING 1-10 OF 65 REFERENCES
Mechanisms of placebo and placebo-related effects across diseases and treatments.
TLDR
Recent research has revealed that these psychosocial-induced biochemical changes in a patient's brain and body in turn may affect the course of a disease and the response to a therapy.
Placebos in clinical practice and research.
TLDR
The authors provide examples in neuropsychiatry, illustrating that objective scientific data and well-considered guidelines may solve the ethical dilemma, and placebo control might even be considered an ethical obligation.
Do "placebo responders" exist?
NONBLIND PLACEBO TRIAL: AN EXPLORATION OF NEUROTIC PATIENTS' RESPONSES TO PLACEBO WHEN ITS INERT CONTENT IS DISCLOSED.
TLDR
The placebo effect should be looked upon as an epiphenomenon of complicated psychological processes, which are far more important than the disarmingly simple means utilized for its realization.
The placebo effect in heart failure.
  • M. Packer
  • Medicine, Psychology
    American heart journal
  • 1990
Placebo response in studies of major depression: variable, substantial, and growing.
TLDR
The response to placebo in published trials of antidepressant medication for MDD is highly variable and often substantial and has increased significantly in recent years, as has the response to medication.
A comprehensive review of the placebo effect: recent advances and current thought.
TLDR
The demonstration of the involvement of placebo mechanisms inclinical trials and routine clinical practice has highlighted interesting considerations for clinical trial design and opened up opportunities for ethical enhancement of these mechanisms in clinical practice.
Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment.
TLDR
Although placebos had no significant effects on objective or binary outcomes, they had possible small benefits in studies with continuous subjective outcomes and for the treatment of pain.
Evidence for placebo effects on physical but not on biochemical outcome parameters: a review of clinical trials
TLDR
It is suggested that placebo interventions can improve physical disease processes of peripheral organs more easily and effectively than biochemical processes.
...
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