Would modulation of intracellular Ca2+ be antiarrhythmic?


Under several types of conditions, reversal of steps of excitation-contraction coupling (RECC) can give rise to nondriven electrical activity. In this review we explore those conditions for several cardiac cell types (SA, atrial, Purkinje, ventricular cells). We find that abnormal spontaneous Ca2+ release from intracellular Ca2+ stores, aberrant Ca2+ influx… (More)


Cite this paper

@article{Boyden2005WouldMO, title={Would modulation of intracellular Ca2+ be antiarrhythmic?}, author={Penelope A. Boyden and Hendrick E D J ter Keurs}, journal={Pharmacology & therapeutics}, year={2005}, volume={108 2}, pages={149-79} }