Worms and allergy

@article{Carvalho2006WormsAA,
  title={Worms and allergy},
  author={Edgar Marcelino de Carvalho and Leonardo Soares Bastos and Maria Ilma Araújo},
  journal={Parasite Immunology},
  year={2006},
  volume={28}
}
Worms and asthma are associated with a type 2 immune response, but evidence has accumulated that helminth infection is negatively associated with atopy, prevalence of allergic diseases and severity of asthma. One important difference between these polarized type 2 responses is that in allergy modulation of the immunological response is not appropriate, whereas in infection with helminths, several host mechanisms down‐regulate the host immune response. As a result, patients infected with worms… 
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TLDR
The evidence supporting the idea that helminths of the phylum Nematoda (nematodes) may protect against the development of autoimmunity and allergy is reviewed.
Evidence for a Modified Th 2-like response during c hronic helminth infections in school-age children from the rural tropics of Ecuador ”
TLDR
Data suggest that during chronic/high burden helminth infections modified TH2 mechanisms might be setting up which eventually could lead to immune response modulation, which could explain ambiguous associations between helminths infections and allergen conditions.
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