Worms and allergy

@article{Carvalho2006WormsAA,
  title={Worms and allergy},
  author={E. M. Carvalho and Luciana S. Bastos and Maria Ilma Araújo},
  journal={Parasite Immunology},
  year={2006},
  volume={28}
}
Worms and asthma are associated with a type 2 immune response, but evidence has accumulated that helminth infection is negatively associated with atopy, prevalence of allergic diseases and severity of asthma. One important difference between these polarized type 2 responses is that in allergy modulation of the immunological response is not appropriate, whereas in infection with helminths, several host mechanisms down‐regulate the host immune response. As a result, patients infected with worms… 

Atopic disorders and parasitic infections.

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Purpose of reviewIt is estimated that over 1 billion individuals are infected with helminth parasites worldwide. Epidemiologic studies have pointed to a protective role of helminthic infections in

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  • Biology, Medicine
    Clinical and experimental immunology
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Evidence is provided that the expression of allergic inflammation in different regions of the Tropics may depend partly on local differences in the endemicity of geohelminth infections.

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Recent findings and new concepts relating to the associations between parasites and allergies at the epidemiological, cellular and molecular level are discussed.
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