Worldwide human relationships inferred from genome-wide patterns of variation.

@article{Li2008WorldwideHR,
  title={Worldwide human relationships inferred from genome-wide patterns of variation.},
  author={Jun Z. Li and Devin M Absher and Hua Tang and Audrey M. Southwick and Amanda M. Casto and Sohini Ramachandran and Howard M. Cann and Gregory S Barsh and Marcus W. Feldman and Luigi Luca Cavalli-Sforza and Richard M Myers},
  journal={Science},
  year={2008},
  volume={319 5866},
  pages={
          1100-4
        }
}
Human genetic diversity is shaped by both demographic and biological factors and has fundamental implications for understanding the genetic basis of diseases. We studied 938 unrelated individuals from 51 populations of the Human Genome Diversity Panel at 650,000 common single-nucleotide polymorphism loci. Individual ancestry and population substructure were detectable with very high resolution. The relationship between haplotype heterozygosity and geography was consistent with the hypothesis of… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 1,127 CITATIONS, ESTIMATED 72% COVERAGE

Mathematical Constraints on FST: Biallelic Markers in Arbitrarily Many Populations.

VIEW 5 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

The genetic admixture in Tibetan-Yi Corridor.

VIEW 6 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Correction: Strong Selection at MHC in Mexicans since Admixture

VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Correction: Strong Selection at MHC in Mexicans since Admixture.

VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc.

VIEW 6 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Rare Variation Facilitates Inferences of Fine-Scale Population Structure in Humans

VIEW 9 EXCERPTS
CITES METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2008
2020

CITATION STATISTICS

  • 204 Highly Influenced Citations

  • Averaged 68 Citations per year from 2017 through 2019

  • 2% Increase in citations per year in 2019 over 2018

References

Publications referenced by this paper.
SHOWING 1-2 OF 2 REFERENCES

M

  • S. Ramachandran, O. Deshpande, C. C. Roseman, N. A. Rosenberg
  • W. Feldman et al., Proc. Natl. Acad. Sci. U S A 102,
  • 1594
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

A B C D Figure S5 A B Figure S5 C Figure S6 YRI Ancestral Allele Freq. C o u n ts

  • N. A. Rosenberg, S. Mahajan, S. Ramachandran, C. Zhao, J. K. Pritchard
  • PLoS Genet. 1,
  • 2005
VIEW 2 EXCERPTS