Worldwide epidemiology of hepatitis A virus infection.

  title={Worldwide epidemiology of hepatitis A virus infection.},
  author={Craig N. Shapiro and H. S. Margolis},
  journal={Journal of hepatology},
  volume={18 Suppl 2},
Patterns of hepatitis A virus (HAV) infection and clinical disease differ worldwide, and correlate with socioeconomic conditions (and hygienic and sanitary conditions) of each geographic area. In least developed countries with very poor sanitary and hygienic conditions, HAV spreads readily, and most persons are infected as young children. Because most persons become infected at an age when HAV infection is often asymptomatic, reported disease rates in these areas are low and outbreaks of… CONTINUE READING

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