Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

  title={Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation},
  author={Jun Z. Li and Devin M Absher and Hua Tang and Audrey M. Southwick and Amanda M. Casto and Sohini Ramachandran and Howard M. Cann and Gregory S. Barsh and Marcus W. Feldman and Luigi Luca Cavalli-Sforza and Richard M. Myers},
  pages={1100 - 1104}
Human genetic diversity is shaped by both demographic and biological factors and has fundamental implications for understanding the genetic basis of diseases. We studied 938 unrelated individuals from 51 populations of the Human Genome Diversity Panel at 650,000 common single-nucleotide polymorphism loci. Individual ancestry and population substructure were detectable with very high resolution. The relationship between haplotype heterozygosity and geography was consistent with the hypothesis of… 

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Title : Genes mirror geography within Europe

Despite low average levels of genetic differentiation among Europeans, there is a close correspondence between genetic and geographic distances; indeed, a geographical map of Europe arises naturally as an efficient two-dimensional summary of genetic variation in Europeans.

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