Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

@article{Li2008WorldwideHR,
  title={Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation},
  author={J. Li and D. Absher and H. Tang and Audrey M. Southwick and Amanda M. Casto and S. Ramachandran and H. Cann and G. Barsh and M. Feldman and L. Cavalli-Sforza and R. Myers},
  journal={Science},
  year={2008},
  volume={319},
  pages={1100 - 1104}
}
  • J. Li, D. Absher, +8 authors R. Myers
  • Published 2008
  • Medicine, Biology
  • Science
  • Human genetic diversity is shaped by both demographic and biological factors and has fundamental implications for understanding the genetic basis of diseases. We studied 938 unrelated individuals from 51 populations of the Human Genome Diversity Panel at 650,000 common single-nucleotide polymorphism loci. Individual ancestry and population substructure were detectable with very high resolution. The relationship between haplotype heterozygosity and geography was consistent with the hypothesis of… CONTINUE READING

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