World Health Organization International Standard to Harmonize Assays for Detection of Hepatitis E Virus RNA

@inproceedings{Baylis2013WorldHO,
  title={World Health Organization International Standard to Harmonize Assays for Detection of Hepatitis E Virus RNA},
  author={Sally A. Baylis and Johannes Bluemel and Saeko Mizusawa and Keiji Matsubayashi and Hidekatsu Sakata and Yoshiaki Okada and Claudius Micha Nuebling and K. M. Hanschmann},
  booktitle={Emerging infectious diseases},
  year={2013}
}
Nucleic acid amplification technique-based assays are a primary method for the detection of acute hepatitis E virus (HEV) infection, but assay sensitivity can vary widely. To improve interlaboratory results for the detection and quantification of HEV RNA, a candidate World Health Organization (WHO) International Standard (IS) strain was evaluated in a collaborative study involving 23 laboratories from 10 countries. The IS, code number 6329/10, was formulated by using a genotype 3a HEV strain… CONTINUE READING
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