Working together: interactions between vaccine antigens and adjuvants.

  title={Working together: interactions between vaccine antigens and adjuvants.},
  author={Christopher B Fox and R. M. J. Kramer and V LucienBarnes and Quinton M. Dowling and Thomas S. Vedvick},
  journal={Therapeutic advances in vaccines},
  volume={1 1},
The development of vaccines containing adjuvants has the potential to enhance antibody and cellular immune responses, broaden protective immunity against heterogeneous pathogen strains, enable antigen dose sparing, and facilitate efficacy in immunocompromised populations. Nevertheless, the structural interplay between antigen and adjuvant components is often not taken into account in the published literature. Interactions between antigen and adjuvant formulations should be well characterized to… CONTINUE READING
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