Working memory and executive function: evidence from neuroimaging

  title={Working memory and executive function: evidence from neuroimaging},
  author={Patricia A. Carpenter and Marcel Adam Just and Erik D. Reichle},
  journal={Current Opinion in Neurobiology},

Working memory and the brain: a review of models, and clinical and neuroimaging studies

This paper presents a review of literature aimed at a general discussion on memory, working memory (WM) and the brain, based on a three-pronged source of evidence from clinical, behavioral, and, more

FROST: A Distributed Neurocomputational Model of Working Memory Maintenance

A computational model of WM, called FROST, is proposed in which the representation of items and spatial positions is encoded in the lateral prefrontal cortex, and successfully accounts for a wide variety of WM data, including single-cell recording data and human behavioral data.

Are central executive functions working in patients with focal frontal lesions?

Executive functions and their disorders.

  • R. Elliott
  • Psychology, Biology
    British medical bulletin
  • 2003
The emerging view suggests that executive function is mediated by dynamic and flexible networks, that can be characterised using functional integration and effective connectivity analyses, compatible with the clinical presentation of executive dysfunction associated with a range of pathologies, and with evidence that recovery of executive function can occur after traumatic brain injury.

Measuring Central Executive Functioning: What's in a Reading Span?

The results suggest that, rather than unitary central executive or processing speed functions underlying RST performance, at least two factors, manipulation capacity and susceptibility to interference, underlie the task.

General intelligence and memory span: Evidence for a common neuroanatomic framework

Results indicate that a common anatomic framework for these constructs implicates mainly frontal grey matter regions belonging to Brodmann area (BA) 10 and left middle frontal gyrus and, to a lesser degree, the right inferior parietal lobule (BA 40).

Simultaneous interpreting and working memory executive control

Working memory is a complex cognitive component responsible for maintenance of information during processing. Interpreting research has so far focused on working memory capacity rather than on the

Working memory load modulation of parieto‐frontal connections: Evidence from dynamic causal modeling

It is suggested that working memory load modulates brain connectivity in a parieto‐frontal network, and may reflect altered neuronal processes, e.g., information processing or error monitoring, with the change in working memory Load.

Working memory capacity, indirect semantic priming, and stroop interference: pattern of interindividual prefrontal performance differences in healthy volunteers.

The study shows that prefrontal functioning varies interindividually, forming patterns of performance differences, which suggest that working memory, executive control, and semantic retrieval are functionally related to some extent.



Imaging Cognition: An Empirical Review of PET Studies with Normal Subjects

PET studies of higher-order cognitive processes, including attention (sustained and selective), perception (of objects, faces, and locations), language (word listening, reading, and production), working memory (phonological and visuo-spatial), semantic memory retrieval, episodic memory retrieval (verbal and nonverbal), priming, and procedural memory are reviewed.

Temporal dynamics of brain activation during a working memory task

Functional magnetic resonance imaging is used to examine brain activation in human subjects during performance of a working memory task and to show that prefrontal cortex along with parietal cortex appears to play a role in active maintenance.

Recent developments in working memory

  • A. Baddeley
  • Psychology
    Current Opinion in Neurobiology
  • 1998

Storage and executive processes in the frontal lobes.

The human frontal cortex helps mediate working memory, a system that is used for temporary storage and manipulation of information and that is involved in many higher cognitive functions. Working

A Parametric Study of Prefrontal Cortex Involvement in Human Working Memory

Functional magnetic resonance imaging is used to probe PFC activity during a sequential letter task in which memory load was varied in an incremental fashion, providing a "dose-response curve" describing the involvement of both PFC and related brain regions in WM function.

The prefrontal cortex: Executive and cognitive functions.

Roberts, theories and models of executive function based on neuropsychological studies in humans, a computational approach to prefrontal cortex, cognitive control and schizophrenia - recent developments and current challenges.

The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive.

  • P. Goldman-Rakic
  • Psychology, Biology
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 1996
This paper focuses on the working memory processor as a specialization of prefrontal cortex and argues that the different areas within prefrontal cortex represent iterations of this function for different information domains, including spatial cognition, object cognition and additionally, in humans, semantic processing.

Maintenance versus Manipulation of Information Held in Working Memory: An Event-Related fMRI Study

In each subject, activity during the delay period was found in both dorsolateral and ventrolateral PFC in both types of trials, however, dorsal/ventral PFC activity was greater in manipulation trials, consistent with the processing model of the functional organization of working memory in PFC.

Physiological characteristics of capacity constraints in working memory as revealed by functional MRI.

It is demonstrated that regionally specific nodes within the working memory network are capacity-constrained in the physiological domain, providing a missing link in current explorations of the capacity characteristics of working memory.