Intravesical gemcitabine therapy for superficial transitional cell carcinoma: results of a Phase II prospective multicenter study.
Expert’s summary: Although radical cystectomy is the recommended curative treatment for patients with muscle-invasive bladder cancer, many patients receive alternative therapies, such as chemotherapy or radiation. In this population-based study, Gore et al compared survival outcomes of invasive bladder cancer patients according to the treatment they received. Only 21% of patients underwent cystectomy. Patients whowere older, who had significant comorbidity, orwhohad to travel longdistances to a surgeon were less likely to have cystectomy. Overall survival was better for patients after cystectomy than for those who underwent alternative treatments.