Women's Trials: The Approval of the First Oral Contraceptive Pill in the United States and Great Britain

@article{Junod2002WomensTT,
  title={Women's Trials: The Approval of the First Oral Contraceptive Pill in the United States and Great Britain},
  author={Suzanne White Junod and Lara V. Marks},
  journal={Journal of the History of Medicine and Allied Sciences},
  year={2002},
  volume={57},
  pages={117 - 160}
}
  • S. JunodL. Marks
  • Published 1 April 2002
  • Medicine
  • Journal of the History of Medicine and Allied Sciences
L'impact medical, social et politique de la pilule contraceptive orale aux Etats-Unis et en Grande-Bretagne est decrit 

The Current Status of Oral Contraceptives: Progress and Recent Innovations.

The current review discusses the clinical characteristics of oral contraceptives, with emphasis on basic pharmacology and the evolution of various contraceptive formulations and regimens.

After 50 years of ethinylestradiol, another oestrogen in combined oral contraceptives

  • J. Alsina
  • Medicine
    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
  • 2010
It is necessary to select patients suitable for vaginal or laparoscopic excision for the administration of IUDs based on prior history and once they provide informed consent for surgery, according to the manufacturer.

“Pregnancy and labour cause more deaths than oral contraceptives”: The debate on the pill in the Spanish press in the 1960s and 1970s

Analysis of debates about the contraceptive pill in the Spanish daily newspaper ABC and in two magazines, Blanco y Negro and Triunfo, in the 1960s and 1970s concludes that the debate was much more heterogeneous than might be expected given the Catholic-conservative character of the dictatorship.

Oral contraceptives do not appear to present long-term cancer harms and may even provide protection against some cancers

Lifetime cancer risks and combined oral contraceptives: the Royal College of General Practitioners’ oral contraceptive study suggests that women should choose between these methods to control their fertility.

Peer Reviewed Title: How Pill became a lifestyle drug: The pharmaceutical industry and birth control in the United States since 1960

The stalled progress in contraceptive development in the decades following the advent of the Pill is reviewed and the finetuning of the market for oral contraceptives in the 1990s and 2000s is examined.

The social life of the Pill : an ethnography of contraceptive pill users in a central London family planning clinic

This thesis contributes to the anthropological theory of "natural facts" by providing an example of how they are mobilised by women using the pill and suggests that " natural facts" continue to provide a privileged ground for femininity.

Hormonal Contraception and the Informed Consent*

The use of the informed consent to provide patients with information on the medical and ethical risks of oral contraceptives is discussed and FABMs and abstinence are presented as effective, safe, and licit preferences to oral contraceptives.

History of oral contraception

  • M. Dhont
  • Medicine
    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
  • 2010
All's well that ends well: recent reports have substantiated the multiple noncontraceptive health benefits paving the way for a bright future for this 50-year-old product.
...

References

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The Birmingham Oral Contraceptive Trial

The method was highly acceptable to the women and no drop-outs resulted from side effects and it is suggested that with the 2.5 mg dose of norethynodrel the estrogen concentration becomes critical and may merely delay ovulation rather than inhibit it.

SMALL-SCALE CLINICAL TRIALS OF PROGESTOGENS FOR CONTROL OF CONCEPTION.

Evaluation of clinical progestational potency evidence of cycle control and inhibition of ovulation and observations on the use of products tested as oral contraceptives are reported. 820 cycles in

History of the first oral contraceptive.

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  • Medicine, Biology
    Journal of toxicology and environmental health
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The final compound was the original 10 mg Enovid tablet which led to widespread acceptance of family planning as a socially acceptable procedure and is a milestone in contraceptive research.

Clinical Trials of Oral Contraceptives*

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  • Medicine
    British medical journal
  • 1961
The number of cycles with breakthrough bleeding was less with higher doses of norethynodrel and EE although patients transferred to the higher dose did not show an improvement in breakthrough bleeding.

Risk of thromboembolic disease in women taking oral contraceptives. A preliminary communication to the Medical Research Council by a Subcommittee.

In 1966 an expert committee of the World Health Organization concluded that no cause-and-effect relationship has been established either by available statistics or by experimental evidence on the development of thromboembolic disease in women taking oral contraceptives.

OVULATION INHIBITORS: LARGE-SCALE CLINICAL TRIALS.

  • E. Mears
  • Medicine
    International journal of fertility
  • 1964
In England 24 different tablets incorporating 9 different progestogens are being studied in a central trial; there are large-scale trials in 9 clinics using 10 different products with 1200 patients

Investigation of Relation between Use of Oral Contraceptives and Thromboembolic Disease. A Further Report

The trend in hospital admissions for venous thromboembolism with time corresponded to the trend in the use of oral contraceptives, and there was no evidence to suggest that the number of admissions was affected by publicity about the risk of using the preparations.

Disciplining Reproduction: Modernity, American Life Sciences, and the Problems of Sex

This volume traces the complicated paths through which physiological approaches to reproduction led to endocrinological approaches, creating along the way new technoscientific products from
...