Wolffish antifreeze protein genes are primarily organized as tandem repeats that each contain two genes in inverted orientation.

@article{Scott1988WolffishAP,
  title={Wolffish antifreeze protein genes are primarily organized as tandem repeats that each contain two genes in inverted orientation.},
  author={Gregory K Scott and P H Hayes and Garth L. Fletcher and Peter L Davies},
  journal={Molecular and cellular biology},
  year={1988},
  volume={8 9},
  pages={3670-5}
}
The antifreeze protein genes of the wolffish (Anarhichas lupus) constitute a large multigene family of 80 to 85 copies, which can be classified into two sets. One-third of the genes were linked but irregularly spaced. The other two-thirds were organized as 8-kilobase-pair (kbp) tandem direct repeats that each contained two genes in inverted orientation; DNA sequence analysis suggests that both genes are functional. Except for a single region specific to each gene, the genes and their immediate… CONTINUE READING
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