Wolbachia surface protein (WSP) inhibits apoptosis in human neutrophils.

  title={Wolbachia surface protein (WSP) inhibits apoptosis in human neutrophils.},
  author={Chiara Bazzocchi and Stefano Comazzi and Roberta Santoni and Claudio Bandi and Claudio Genchi and Michele Mortarino},
  journal={Parasite immunology},
  volume={29 2},
Polymorphonuclear cells (PMNs) are essential for the innate immune response against invading bacteria. At the same time, modulation of PMNs' apoptosis or cell death by bacteria has emerged as a mechanism of pathogenesis. Wolbachia bacteria are Gram-negative endosymbionts of filarial nematodes and arthropods, phylogenetically related to the genera Anaplasma, Ehrlichia and Neorickettsia (family Anaplasmataceae). Although several pathogens are known to interfere with apoptosis, there is only… CONTINUE READING
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