Wolbachia density and virulence attenuation after transfer into a novel host.

  title={Wolbachia density and virulence attenuation after transfer into a novel host.},
  author={Elizabeth A McGraw and David J Merritt and J N Droller and Scott L O'Neill},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={99 5},
The factors that control replication rate of the intracellular bacterium Wolbachia pipientis in its insect hosts are unknown and difficult to explore, given the complex interaction of symbiont and host genotypes. Using a strain of Wolbachia that is known to over-replicate and shorten the lifespan of its Drosophila melanogaster host, we have tracked the evolution of replication control in both somatic and reproductive tissues in a novel host/Wolbachia association. After transinfection (the… CONTINUE READING
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