Wolbachia and Virus Protection in Insects

  title={Wolbachia and Virus Protection in Insects},
  author={Lauren M. Hedges and Jeremy C Brownlie and Scott L O'Neill and Karyn N. Johnson},
  pages={702 - 702}
Wolbachia pipientis bacteria are common endosymbionts of insects that are best known for their ability to increase their prevalence in populations by manipulating host reproductive systems. However, there are examples of Wolbachia that exist in nature that seem to induce no reproductive parasitism trait and yet are able to invade populations. We demonstrate a fitness benefit for Wolbachia-infected insects that may explain this paradox. Drosophila melanogaster flies infected with Wolbachia are… Expand
Wolbachia and arbovirus inhibition in mosquitoes.
  • S. Sinkins
  • Biology, Medicine
  • Future microbiology
  • 2013
Modulation of autophagy and lipid metabolism, and intracellular competition between viruses and bacteria for lipids, provide promising hypotheses for the mechanism of inhibition in Aedes aegypti. Expand
Wolbachia Infections in Arthropod Hosts
This chapter will review the current state of knowledge of Wolbachia reproductive phenotypes and WolbachIA -induced pathogen interference, and discuss these in the context of applied use of Wolachia for arthropod-borne disease and pest control. Expand
Identification of Wolbachia Strains in Mosquito Disease Vectors
Wolbachia bacteria are identified in Kenyan populations of the yellow fever vector Aedes bromeliae and its relative Aedes metallicus, and in Mansonia uniformis and Mansonia africana, which are vectors of lymphatic filariasis. Expand
Wolbachia pipientis: an expanding bag of tricks to explore for disease control.
The evidence for the idea that the insect immune response is responsible for the pathogen inhibition is evaluated and the added value of maternally inherited, endosymbiotic bacteria for biocontrol strategies is highlighted. Expand
Titer regulation in arthropod-Wolbachia symbioses.
Both environmental and biological factors modulating Wolbachia titers in arthropods are reviewed to consider fine regulation of bacterial titers as a milestone in host-endosymbiont interplay. Expand
Wolbachia in a major African crop pest increases susceptibility to viral disease rather than protects.
It is suggested that rather than protecting their lepidopteran host from viral infection, Wolbachia instead make them more susceptible to virus infection, which potentially has implications for the biological control of other insect crop pests. Expand
Wolbachia‐mediated protection against viruses in the invasive pest Drosophila suzukii
It is found that the Wolbachia strain wSuz, which naturally infects Drosophila suzukii, can increase host survival upon infection with these two viruses, suggesting that it confers resistance to the viruses rather than allowing the flies to tolerate infection. Expand
The Impact of Wolbachia on Virus Infection in Mosquitoes
Research on the prevalence of Wolbachia in mosquito vector species and the impact of antiviral effects in both naturally and artificially Wolbachio-infected mosquitoes is outlined. Expand
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium
It is suggested that this Wolbachia-mediated pathogen interference may work synergistically with the life-shortening strategy proposed previously to provide a powerful approach for the control of insect transmitted diseases. Expand
Wolbachia-based strategies to control insect pests and disease vectors
This review summarizes recent developments in Wolbachia research, specifically within the context of applied Wolbachian-based strategies used to suppress or modify natural insect populations. Expand


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Analysis of long-term lab stocks together with wild-caught flies indicates that one of these variants has replaced the others globally within the last century, the first report of a global replacement of a Wolbachia strain in an insect host species. Expand
Population dynamics of the Wolbachia infection causing cytoplasmic incompatibility in Drosophila melanogaster.
It is shown that the level of incompatibility under field conditions was much weaker than in the laboratory, and simple models suggest that the infection probably provides a fitness benefit for the host in order to persist in populations. Expand
Host-pathogen interactions in drosophila: new tricks from an old friend
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The evolution of heritable symbionts cytoplasmic incompatability in insects inherited microorganisms and sex determination of arthropod hosts wolbachia induced parthenogenesis cytoplasmic sex ratioExpand
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This is the first attempt since 1925 to publish a comprehensive account of the biology and genetics of Drosophila and it aims to collate the dauntingly large literature on the subject and to make more accessible the private language ot the Dosophilist. Expand
The novel genome organization of the insect picorna-like virus Drosophila C virus suggests this virus belongs to a previously undescribed virus family.
The finding of this novel genome organization for DCV shows that this virus is not a member of the Picornaviridae as previously thought, but belongs to a distinct and hitherto unrecognized virus family. Expand
Materials and methods are available as supporting material on Science Online