Wogonin suppresses human alveolar adenocarcinoma cell A549 migration in inflammatory microenvironment by modulating the IL-6/STAT3 signaling pathway.

@article{Zhao2015WogoninSH,
  title={Wogonin suppresses human alveolar adenocarcinoma cell A549 migration in inflammatory microenvironment by modulating the IL-6/STAT3 signaling pathway.},
  author={Yue Zhao and Jing Yao and Xiaoping Wu and Lu Zhao and Yu-Xin Zhou and Yi Zhang and Qidong You and Qinglong Guo and Na Lu},
  journal={Molecular carcinogenesis},
  year={2015},
  volume={54 Suppl 1},
  pages={
          E81-93
        }
}
Increasing evidence from various clinical and experimental studies has demonstrated that the inflammatory microenvironment facilitates tumor metastasis. Clinically, it will be a promising choice to suppress tumor metastasis by targeting inflammatory microenvironment. Our previous studies have demonstrated that wogonin (a bioflavonoid isolated from the traditional Chinese medicine of Huang-Qin) possesses the anti-metastatic and anti-inflammatory activity, but we have little idea about its… CONTINUE READING
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