Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity.

@article{Piao2008WogoninIM,
  title={Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity.},
  author={Hua Zi Piao and In Young Choi and Jin-sun Park and Hee-Sun Kim and Jae Hoon Cheong and Kun Ho Son and Su jin Jeon and Kwang Ho Ko and Won-Ki Kim},
  journal={International immunopharmacology},
  year={2008},
  volume={8 12},
  pages={
          1658-62
        }
}
Previously, we and others have demonstrated that wogonin, an active component from the root of Scutellaria baicalensis Georgi, has a neuroprotective effect in cerebral ischemic insult. The neuroprotective effect of wogonin may at least in part be due to its anti-inflammatory properties. Microglial cells, well-known residential macrophages in the central nervous system, migrate to the ischemic lesion and play a pivotal role in the development of chronic inflammation. In the present study, we… CONTINUE READING

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