Wntless, a Conserved Membrane Protein Dedicated to the Secretion of Wnt Proteins from Signaling Cells

@article{Bnziger2006WntlessAC,
  title={Wntless, a Conserved Membrane Protein Dedicated to the Secretion of Wnt Proteins from Signaling Cells},
  author={C. B{\"a}nziger and D. Soldini and C. Sch{\"u}tt and P. Zipperlen and G. Hausmann and K. Basler},
  journal={Cell},
  year={2006},
  volume={125},
  pages={509-522}
}
Cell-cell communication via Wnt signals represents a fundamental means by which animal development and homeostasis are controlled. The identification of components of the Wnt pathway is reaching saturation for the transduction process in receiving cells but is incomplete concerning the events occurring in Wnt-secreting cells. Here, we describe the discovery of a novel Wnt pathway component, Wntless (Wls/Evi), and show that it is required for Wingless-dependent patterning processes in Drosophila… Expand
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