Wnt9A Induction Linked to Suppression of Human Colorectal Cancer Cell Proliferation
@article{Ali2016Wnt9AIL, title={Wnt9A Induction Linked to Suppression of Human Colorectal Cancer Cell Proliferation}, author={I. Ali and B. Medegan and D. Braun}, journal={International Journal of Molecular Sciences}, year={2016}, volume={17} }
Most studies of Wnt signaling in malignant tissues have focused on the canonical Wnt pathway (CWP) due to its role in stimulating cellular proliferation. The role of the non-canonical Wnt pathway (NCWP) in tissues with dysregulated Wnt signaling is not fully understood. Understanding NCWP’s role is important since these opposing pathways act in concert to maintain homeostasis in healthy tissues. Our preliminary studies demonstrated that LiCl inhibited proliferation of primary cells derived from… CONTINUE READING
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