Wnt5a participates in distal lung morphogenesis.

  title={Wnt5a participates in distal lung morphogenesis.},
  author={Changgong Li and Jing Xiao and Khadija Hormi and Zea Borok and Parviz Minoo},
  journal={Developmental biology},
  volume={248 1},
Operational parallels in overall mechanisms of three-dimensional patterning of vertebrate organs are becoming increasingly apparent. Many key mediators, such as FGFs, BMPs, and sonic hedgehog, participate in organization of a number of organs, including the lungs, which exhibit a defined proximodistal (P-D) polarity. Recently, Wnt5a a member of the wingless family of signaling molecules involved in cell proliferation, differentiation, and organogenesis, was shown to underlie the outgrowth and P… CONTINUE READING
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