Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.

@article{Majumdar2003Wnt11AR,
  title={Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.},
  author={Arindam Majumdar and Seppo J Vainio and Andreas Kispert and Jill P. McMahon and Andrew P. McMahon},
  journal={Development},
  year={2003},
  volume={130 14},
  pages={3175-85}
}
Reciprocal cell-cell interactions between the ureteric epithelium and the metanephric mesenchyme are needed to drive growth and differentiation of the embryonic kidney to completion. Branching morphogenesis of the Wolffian duct derived ureteric bud is integral in the generation of ureteric tips and the elaboration of the collecting duct system. Wnt11, a member of the Wnt superfamily of secreted glycoproteins, which have important regulatory functions during vertebrate embryonic development, is… CONTINUE READING
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